Rapid sample classification using an open port sampling interface coupled with liquid introduction atmospheric pressure ionization mass spectrometry

Atmospheric pressure free liquid infrared MALDI mass spectrometry: toward a combined ESI/ MALDI-liquid chromatography interface.

A new atmospheric pressure (AP)-MALDI-type interface has been developed based on a free liquid (FL) microbeam/microdroplets and a mid-infrared optical parametric oscillator (mid-IR OPO). The device is integrated into a standard on-line nanoESI interface. The generation of molecular ions in the gas phase is believed to be the result of a fast (explosive) laser-induced evaporative dispersion(not ...

Characterization of typical chemical background interferences in atmospheric pressure ionization liquid chromatography-mass spectrometry.

The structures and origins of typical chemical background noise ions in positive atmospheric pressure ionization liquid chromatography/mass spectrometry (API LC/MS) are investigated and summarized in this study. This was done by classifying chemical background ions using precursor and product ion scans on most abundant background ions to draw a family tree of the commonly occurring chemical bac...

The use of liquid chromatography-atmospheric pressure ionization-mass spectrometry in water analysis ^ Part I: Achievements

Liquid chromatography-mass spectrometry using atmospheric pressure ionization is dramatically changing the analytical methods, potential and tasks of water analysis. The present status in applying this technique to organic as well as inorganic water constituents and its use in the context of wastewater treatment and drinking water preparation is reviewed. Separation techniques such as reversed-...

Use of atmospheric pressure ionization mass spectrometry in enantioselective liquid chromatography.

Recent advances in mass spectrometry have rendered it an attractive and versatile tool in industrial and academic research laboratories. As a part of this rapid growth, a considerable body of literature has been devoted to the application of mass spectrometry in studies involving enantioselectivity, molecular recognition, and supramolecular chemistry. In concert with separation techniques such ...

Determination of valproic acid in serum by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.